تحلیل و طراحی حسگر فشار داخل جمجمه پیزورزیستیو جدید با حساسیت بالا

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشگاه صنعتی نوشیروانی بابل

2 دانشگاه صنعتی نوشیروانی ، بابل

چکیده

در این مقاله ،حسگر فشار جمجمه پیزورزیستیو ماشینکاری میکرونی جدید برای فشار بین صفر تا mmHg225 برای بیماران آسیب دیده جمجمه ای از جمله تومور های مغزی ،پارکینسون یا صدماتی که در اثر تصادف به جمجمه وارد می شود، تحلیل و طراحی شده است که به روش المان محدود با استفاده از نرم افزار intellisuit شبیه سازی شده است. در حسگر جدید جنس ، ابعاد دیافراگم و ساختار پیزورزیستور‌ها جهت زیست سازگاری ، انعطاف پذیری ، کوچک سازی، ساخت ساده و افزایش حساسیت تغییر یافته اند. شش دیافراگم با جنس های متفاوت از مواد کامپوزیت و غیر کامپوزیت مورد بررسی و مقایسه قرار گرفته اندکه در نتیجه ماده‌ای کامپوزیت با استحکام کششی بالاتر انتخاب شده است. سپس طراحی برای چهار پیزورزیستور که به صورت پل‌وتسون بسته شده اند انجام گرفته است که دو عدد از این پیزورزیستورها به صورت طولی و بدون پیچ قرار گرفته‌اند و دو عدد دیگر به صورت عرضی و دارای یک پیچ هستند تا در مناطق حداکثر تنش قرار گیرند و حساسیتشان افزایش یابد . برای مشاهده تاثیر طول پیزورزیستور ها ، شبیه‌سازی با طول پیزورزیستور‌های مختلف با ابعاد دیافراگم یکسان انجام شده است و نتایج نشان می‌دهد ساختار با طول پیزورزیستور µm300 حساسیت بالاتر (µv/mmHg1164/206)و کاملا خطی ارائه کرده است که نسبت به کارهای گذشته حساسیت بسیار بالایی دارد. همچنین از دیگر ویژگی‌های این ساختار آن است که که کلیه مواد مورد استفاده در حسگر زیست‌سازگارند تا بتوان بدون نگرانی در جمجمه قرارداد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Design and analysis of a Novel Piezoresistive INTRACRANIAL Pressure Sensor with High Sensitivity

نویسندگان [English]

  • Faezah Imani 1
  • Bahram Azizollah Gangi 1
  • Ramazan Ali jafari Talookolaei 2
1 babol noshirvani university of technology
2 Babol Noshirvani University of Technology
چکیده [English]

In this paper, a high sensitive piezoresistive intracranial MEMS (Micro Electro Mechanical system) pressure sensor was analyzed and designed for pressure rage of 0-225 mmHg (0-0.05 MPa). This sensor is designed to diagnose disease like Parkinson, brain edema, brain tumor along with other brain problems that could be seriously harmful to the patient. The MEMS technology can create a small size and high sensitive system in order to minimize the brain damages and complications. Enforcing pressure on diaphragm changes the piezoresistor’s resistance and causes a variation in output voltage. In the new sensor, however, the size and material of the diaphragm along with the structure of piezoresistors have been modified. Different materials were investigated and as a result, a substance with the highest tensile strength was chosen. Then the design was done for 4 piezoresistors forming a Wheatstone bridge while two of them are longitudinal without turn and the others are lateral containing a turn. The simulation was done using the finite element method for different piezoresistor lengths with same size. According to the results, a sensitivity of 206.1164 µv/mmHg is achieved with a completely linear output which shows a significant improvement compared with previous works. Furthermore, one of the important feature of this design is all materials used in new structure, including wires and piezoresistors, are biocompatible.

کلیدواژه‌ها [English]

  • piezoresistive pressure sensor
  • Wheatstone bridge
  • microelectromechanical
  • INTRACRANIAL pressure
  • biocompatible materials
[1] Nirula, R., R. Diaz-Arrastia, K. Brasel, J. A. Weigelt, and K. Waxman. "Safety and efficacy of erythropoietin in traumatic brain injury patients: a pilot randomized trial." Critical care research and practice 2010
[2] Zhang, Xuan, Joshua E. Medow, Bermans J. Iskandar, Fa Wang, Mehdi Shokoueinejad, Joyce Koueik, and John G. Webster. "Invasive and noninvasive means of measuring intracranial pressure: a review." Physiological measurement 38, no. 8 (2017): R143.
[3] Ross, N., and C. A. Eynon. "Intracranial pressure monitoring." Current Anaesthesia & Critical Care 16, no. 4 (2005): 255-261.
[4] Khan, M. Waqas A., Lauri Sydänheimo, Leena Ukkonen, and Toni Björninen. "Inductively powered pressure sensing system integrating a far-field data transmitter for monitoring of intracranial pressure." IEEE Sensors Journal 17, no. 7 (2017): 2191-2197.
[5] Kumar, S. Santosh, and B. D. Pant. "Design principles and considerations for the ‘ideal’silicon piezoresistive pressure sensor: a focused review." Microsystem technologies 20, no. 7 (2014): 1213-1247.
[6] Kang, Seung-Kyun, Rory KJ Murphy, Suk-Won Hwang, Seung Min Lee, Daniel V. Harburg, Neil A. Krueger, Jiho Shin et al. "Bioresorbable silicon electronic sensors for the brain." Nature 530, no. 7588 (2016): 71.
[7] Ganji, Bahram Azizollah, and M. Shahiri-Tabarestani. "A novel high sensitive MEMS intraocular capacitive pressure sensor." Microsystem technologies 19, no. 2 (2013): 187-194.
[8]. Besling, Willem Frederik Adrianus, Martijn Goossens, Jozef Thomas Martinus Van Beek, Peter Gerard Steeneken, and Olaf Wunnicke. "MEMS capacitive pressure sensor." U.S. Patent 9,772,245, issued September 26, 2017.
[9] Kumar, Madhav, and Harish Bhaskaran. "Ultrasensitive room-temperature piezoresistive transduction in graphene-based nanoelectromechanical systems." Nano letters 15, no. 4 (2015): 2562-2567.
[10] Molaei, Somayye, and Bahram Azizollah Ganji. "Design and simulation of a novel RF MEMS shunt capacitive switch with low actuation voltage and high isolation." Microsystem Technologies 23, no. 6 (2017): 1907-1912.
[11] Tabarestani, M. Shahiri, and B. Azizollah Ganji. "Analytical Analysis of Capacitive Pressure Sensor with Clamped Diaphragm." International Journal of Engineering 26, no. 3 (2012): 297-302.
[12] Wu, Z. Z., N. Bhattacharjee, C. Y. Li, J. A. Hartings, R. K. Narayan, and C. H. Ahn. "A new intracranial pressure sensor on polyimide lab-on-a-tube using exchanged polysilicon piezoresistors." In 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII), pp. 1779-1782. IEEE, 2013.
[13] Sattayasoonthorn, Preedipat, Jackrit Suthakorn, Sorayouth Chamnanvej, Jianmin Miao, and A. G. P. Kottapalli. "LCP MEMS implantable pressure sensor for intracranial pressure measurement." In The 7th IEEE International Conference on Nano/Molecular Medicine and Engineering, pp. 63-67. IEEE, 2013.
[14] Meng, Xiawei, and Yulong Zhao. "Packaging a piezoresistive pressure sensor for intracranial pressure monitoring." In SENSORS, 2014 IEEE, pp. 1827-1830. IEEE, 2014.
[15] Mokhtari, Zahra, Reza Sabbaghi-Nadooshan, and Fardad Farokhi. "New Optimization of a Micro Piezoresistive Pressure Sensor at Low Pressure." (2015).
[16] Prasad, G. Ram, Stephen Daniels, D. C. Cameron, B. P. McNamara, Elizabeth Tully, and R. O'Kennedy. "PECVD of biocompatible coatings on 316L stainless steel." Surface and Coatings Technology 200, no. 1-4 (2005): 1031-1035.
[17] Ahn, Jeoung-Hee, Khanh-Hung Nguyen, Yong-Bin Park, Jin-Hwe Kweon, and Jin-Ho Choi. "A numerical study of the high-velocity impact response of a composite laminate using LS-DYNA." International Journal of Aeronautical and Space Sciences 11, no. 3 (2010): 221-226.
[18] Zhang, Meng, and Jukka Pekka Matinlinna. "E-glass fiber reinforced composites in dental applications." Silicon 4, no. 1 (2012): 73-78.
[19] Henderson Jr, James D., Richard H. Mullarky, and Doreen E. Ryan. "Tissue biocompatibility of kevlar aramid fibers and polymethylmethacrylate, composites in rabbits." Journal of biomedical materials research 21, no. 1 (1987): 59-64.
[20] Safri, Syafiqah Nur Azrie, Mohamed Thariq Hameed Sultan, Mohammad Jawaid, and Kandasamy Jayakrishna. "Impact behaviour of hybrid composites for structural applications: A review." Composites Part B: Engineering 133 (2018): 112-121.
[21] Vallittu, Pekka K., Timo O. Närhi, and Leena Hupa. "Fiber glass–bioactive glass composite for bone replacing and bone anchoring implants." Dental Materials 31, no. 4 (2015): 371-381.
[22] Agarwal, Bhagwan D., Lawrence J. Broutman, and K. Chandrashekhara. Analysis and performance of fiber composites. John Wiley & Sons, 2017.
[23] Pourdeyhimi, B., H. D. Wagner, and P. Schwartz. "A comparison of mechanical properties of discontinuous Kevlar 29 fibre reinforced bone and dental cements." Journal of materials science 21, no. 12 (1986): 4468-4474.
[24] Dickson, Andrew N., James N. Barry, Kevin A. McDonnell, and Denis P. Dowling. "Fabrication of continuous carbon, glass and Kevlar fibre reinforced polymer composites using additive manufacturing." Additive Manufacturing 16 (2017): 146-152.
[25] Murphy, Caroline, Krishna Kolan, Wenbin Li, Julie A. Semon, D. E. Day, and Ming-Chuan Leu. "3D bioprinting of stem cells and polymer/bioactive glass composite scaffolds for bone tissue engineering." (2017): 53.
[26] Pourdeyhimi, B., H. H. Robinson, P. Schwartz, and H. D. Wagner. "Fracture toughness of Kevlar 29/poly (methyl methacrylate) composite materials for surgical implantations." Annals of biomedical engineering 14, no. 3 (1986): 277-294.
[27] Lazar, Madalina-Anca, Horatiu Rotaru, Ioana Bâldea, Adina B. Bosca, Cristian P. Berce, Cristina Prejmerean, Doina Prodan, and Radu S. Câmpian. "Evaluation of the biocompatibility of new fiber-reinforced composite materials for craniofacial bone reconstruction." Journal of Craniofacial Surgery 27, no. 7 (2016): 1694-1699.